sevoflurane abuse

sevoflurane abuse

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  • A fatality from sevoflurane abuse

    A case is presented of a 47 year old man who died as a result of sevoflurane abuse Sevoflurane was identified and confirmed by headspace gas chromatography mass spectrometry The heart blood sevoflurane concentration was 16 mg/L and the peripheral blood sevoflurane concentration was

  • Neonatal sevoflurane exposure induces impulsive behavioral

    Jun 20 2020  The chamber was connected to a sevoflurane vaporizer Vapor 2000 Medical Systems Inc Germany and continuously flushed with 60 oxygen balanced nitrogen FIO 2

  • Sevoflurane addiction due to workplace exposure A case

    After cessation of sevoflurane abuse his craving and withdrawal symptoms were severe on the first day and lasted 7 to 9 days Figs 2A and D Compared to the first time there were no significant differences in the patient s craving for sevoflurane and accompanying withdrawal signs Figs 2B C E and F

  • Sevoflurane

    Sevoflurane is a sweet smelling nonflammable highly fluorinated methyl isopropyl ether used as an inhalational anaesthetic for induction and maintenance of general anesthesia After desflurane it is the volatile anesthetic with the fastest onset While its offset may be faster than agents other than desflurane in a few circumstances its offset is more often similar to that of the much

  • The Effects of Fentanyl on Sevoflurane Requirements for

    The MAC awake of sevoflurane obtained in this study was 0 62 This is similar to the determined sevoflurane MAC awake in our previous study In that investigation we showed that fentanyl significantly reduced the MAC awake of sevoflurane at a plasma concentration of 2 ng/ml However this reduction was much smaller than that reported for the

  • Sevoflurane Archives

    Jun 26 2018  A similar case report was published Burrows DL Distribution of sevoflurane in a sevoflurane induced death J Forensic Sci 2004 Mar 49 2 394 7 describing the following The decedent was found lying in a bed with an oxygen mask containing a gauze pad secured to his face Three empty bottles and one partially full bottle of Ultane

  • A survey of inhalational anaesthetic abuse in anaesthesia

    May 09 2008  A survey aiming to quantify drug and alcohol abuse was sent to 304 departments of anaesthesia in the UK and Ireland Thirty nine per cent of the departments that responded reported at least one case of substance abuse in the previous 10 years Thus drug abuse amongst anaesthetists is a growing problem worldwide and requires further study

  • Addressing Substance Use Disorder for Anesthesia Professionals

    agents e g sevoflurane nitrous oxide and intravenous IV anesthetic agents e g propofol which is not classified as a controlled substance are readily available to anesthesia professionals to provide anesthe sia services Even with medication dispensing and

  • Isoflurane Anesthetic Gas Guidelines

    Isoflurane is an eye and skin irritant and central nervous system toxicant Long term exposure may cause chronic or adverse health effects including nausea dizziness fatigue headache irritability reduced mental performance liver and kidney disease and possible reproductive effects sterility infertility miscarriages and birth defects

  • Sevoflurane Indications Side Effects Warnings

    Sep 27 2020  Drugs provides accurate and independent information on more than 24 000 prescription drugs over the counter medicines and natural products This material is provided for educational purposes only and is not intended for medical advice diagnosis or treatment Data sources include IBM Watson Micromedex updated 11 Oct 2021 Cerner Multum updated 1 Nov 2021

  • Sevoflurane abuse

    Jan 19 2013  SevofluraneabuseSubstance related disordersadverse reactionsDeathdrug induced REFERENCE 1 Rosales CM Young T Laster MJ Eger II EI Garg U Sevoflurane concentrations in blood brain and lung after sevoflurane induced death Journal of Forensic Sciences 52 1408 1410 No 6 Nov 2007USA

  • Medical Toxicology of Drug Abuse Synthesized Chemicals

    Mar 20 2012  This book provides a broad reference covering important drugs of abuse including amphetamines opiates and steroids It also covers psychoactive plants such as caffeine peyote and psilocybin It provides chemical structures analytical methods clinical features and treatments of these drugs of abuse serving as a highly useful in depth supplement to a general medical toxicology book

  • Fatality from Sevoflurane Abuse

    A case is presented of a 47 year old man who died as a result of sevoflurane abuse Sevoflurane was identified and confirmed by headspace gas chromatography mass spectrometry The heart blood sevoflurane concentration was 16 mg/L and the peripheral blood sevoflurane concentration was

  • Considerations in Selecting an Inhaled Anesthetic Agent

    Oct 14 2021  Desflurane isoflurane and sevoflurane cause much less myocardial depression than halothane Furthermore with K A s history of alcohol abuse there

  • Fulminant Hepatic Failure in the Course of an Outpatient

    A 20 year old man underwent an outpatient general anesthetic procedure with sevoflurane for the correction of a bilateral gynecomastia The patient had been first exposed to sevoflurane two years before without any complication He presented an overweight with a body mass index BMI of 31 4 kg/m 2 and had an episode of #x201cbinge #x201d drinking a few days before anesthesia

  • Systemic and regional hemodynamic effects of a high

    Jun 09 2005  Cocaine abuse has been linked to penetrating and blunt trauma requiring surgical treatment Although the cardiovascular effects of cocaine are well studied particularly its association with arrhythmia myocardial infarction and sudden death little is known about the effects of cocaine abuse on splanchnic perfusion and the potential undesirable interaction with volatile anesthetics

  • Effects of Alcohol History on Effects of Sevoflurane and

    Sep 21 1999  The purpose of this study is to evaluate the effects of alcohol history on the subjective and reinforcing effects of sevoflurane and nitrous oxide in healthy volunteers All subjects underwent psychomotor testing during 4 sessions of placebo drug/placebo and choice of intervention

  • Halogenated Ethers Enflurane Isoflurane Methoxyflurane

    Feb 02 2012  Halogenated Ethers Enflurane Isoflurane Methoxyflurane Sevoflurane Donald G Barceloux Department of Emergency Medicine University of California at

  • Reinforcing and subjective effects of the volatile

    Sevoflurane is a volatile anesthetic that is chemically similar to volatile substances of abuse and can be safely administered to humans in laboratory

  • Sevoflurane Concentrations in Blood Brain and Lung After

    Oct 18 2007  Sevoflurane is a volatile nonflammable fluorinated methyl isopropyl ether inhaled anesthetic chemically related to desflurane and isoflurane The incidence of abuse of sevoflurane is lower than that of other drugs of abuse possibly due to its inaccessibility to the general public and less pleasurable and addicting effects

  • A fatal case of sevoflurane abuse

    Nov 01 2008  A fatality from sevoflurane abuse Levine B Cox D Jufer Phipps RA Li L Jacobs A Fowler D J Anal Toxicol 8 534 536 2007 MED Sevoflurane concentrations in blood brain and lung after sevoflurane induced death Rosales CM Young T

  • The Controlled Substances Act

    The Controlled Substances Act CSA places all substances which were in some manner regulated under existing federal law into one of five schedules This placement is based upon the substance s medical use potential for abuse and safety or dependence liability More information can be found in Title 21 United States Code USC Controlled Substances Act

  • Anesthetic gases in medical settings

    Halogenated anesthetics such as sevoflurane and desflurane are typically administered in combination with nitrous oxide to produce surgical levels of anesthesia Anesthetic gases and vapors that leak into the surrounding room are considered waste anesthetic gases WAGs More than 250 000 healthcare workers may be exposed to WAGs and are at

  • The Controlled Substances Act

    The Controlled Substances Act CSA places all substances which were in some manner regulated under existing federal law into one of five schedules This placement is based upon the substance s medical use potential for abuse and safety or dependence liability More information can be found in Title 21 United States Code USC Controlled Substances Act

  • Sevoflurane addiction due to workplace exposure A case

    Patient concerns An addictive young male anesthesiologist who was long term abuse with sevoflurane after 4 years occupational exposure A 28 year old anesthesiologist on duty was found deeply sleep in the locker room and coved his nose with Gauze with high concentration of sevoflurane He was found addiction to sevoflurane second time

  • Sevoflurane

    Sevoflurane is a sweet smelling nonflammable highly fluorinated methyl isopropyl ether used as an inhalational anaesthetic for induction and maintenance of general anesthesia After desflurane it is the volatile anesthetic with the fastest onset While its offset may be faster than agents other than desflurane in a few circumstances its offset is more often similar to that of the much

  • Fatal accident caused by isoflurane abuse

    A case is presented of a 47 year old man who died as a result of sevoflurane abuse Sevoflurane was identified and confirmed by headspace gas chromatography mass spectrometry

  • TESTING THE ABUSE POTENTIAL OF SEVOFLURANE IN HEALTHY

    Inhalant abuse including abuse of inhaled anesthetics such as nitrous oxide continues to be a serious problem throughout the world We examined the rewarding effects in humans of sevoflurane a volatile inhaled general anesthetic Such an assessment may indicate the potential for abuse of sevoflurane by anesthesia personnel or others who have

  • STOLEN ANESTHETIC VAPORS

    A similar case report was published Burrows DL Distribution of sevoflurane in a sevoflurane induced death J Forensic Sci 2004 Mar 49 2 394 7 describing the following The decedent was found lying in a bed with an oxygen mask containing a gauze pad secured to his face Three empty bottles and one partially full bottle of Ultane

  • Ultane Sevoflurane Uses Dosage Side Effects

    Aug 07 2020  Sevoflurane is nonflammable and nonexplosive as defined by the requirements of International Electrotechnical Commission 601 2 13 Sevoflurane is a clear colorless liquid containing no additives Sevoflurane is not corrosive to stainless steel brass aluminum nickel plated brass chrome plated brass or copper beryllium Sevoflurane is

  • The Effect of Sevoflurane and Isoflurane Anesthesia on

    studied Patients with a history of substance abuse or gastroesophageal reflux were excluded The study consisted of two parts 1 EEG study after inhaled induction with sevoflurane anesthesia EEG recorded interictal spike activity was compared with awake recordings and

  • Isoflurane Side Effects Common Severe Long Term

    Nov 13 2020  Drugs provides accurate and independent information on more than 24 000 prescription drugs over the counter medicines and natural products This material is provided for educational purposes only and is not intended for medical advice diagnosis or treatment Data sources include IBM Watson Micromedex updated 11 Oct 2021 Cerner Multum updated 1 Nov 2021

  • Reinforcing and subjective effects of the volatile

    Sevoflurane is a volatile anesthetic that is chemically similar to volatile substances of abuse and can be safely administered to humans in laboratory

  • Reinforcing and subjective effects of the volatile

    Nov 11 2004  Sevoflurane is a volatile anesthetic that is chemically similar to volatile substances of abuse and can be safely administered to humans in laboratory research In this study the reinforcing and subjective effects of five concentrations of sevoflurane 0 0 2 0 4 0 6 0 8 sevoflurane in O2 were studied in 20 non drug abusers

  • A Fatality from Sevoflurane Abuse Journal of Analytical

    Oct 01 2007  A case is presented of a 47 year old man who died as a result of sevoflurane abuse Sevoflurane was identified and confirmed by headspace gas chromatography mass spectrometry The heart blood sevoflurane concentration was 16 mg/L and the peripheral blood sevoflurane concentration was 8 0 mg/L No drugs or other volatile substances were found in the heart blood

  • Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic

    Sep 21 1999  Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations11 The safety and scientific validity of this study is the responsibility of the study sponsor and investigators Listing a study does not mean it has been evaluated by the U S Federal Government